Anivia vs Lissandra MID Matchup Guide | LaneStomp

Back to matchup selector

Champion

Opponent

RoleGenerate matchup

Anivia

VS

Mid

Lissandra

Anivia vs Lissandra

Updated Jun 5, 2026

Overview

Anivia is a control mage with medium lane pressure and low early agency, aiming to farm safely and use waveclear to zone Lissandra.
Focus on denying Lissandra easy all-ins by maintaining spacing and forcing her to commit into your (Q) and (W) for picks.

Trading pattern

Initiate trades by landing (Q) to set up (E) for max damage, using (W) to block Lissandra's escape or force her into your (Q).
Avoid trading when (Q) is on cooldown, as missing it leaves you vulnerable to Lissandra's engage.
Punish Lissandra if she uses (E) forward without safe recast options or when (R) is down.

Danger windows

Be cautious when (R) is available, as she can lock you down or deny your all-in attempts.
Avoid extended trades or aggressive positioning when your (Q) is down to prevent being punished.
Losing flash greatly increases risk to (E) engage and (W) root; preserve it for survival.

Early game

Use (Q) and (W) to control the wave and punish Lissandra if she steps too close, avoiding extended trades before level 6.
Respect (W) root and (R) stun by keeping distance and not overextending without flash.
Prioritize farming and avoid risky trades since Lissandra can engage with (E) plus (R).

Power spikes

After level 6 and first mana/AP item, use (R) to zone and force fights on your terms, making it hard for Lissandra to safely engage.
Respect Lissandra's level 6 (R) for lockdown and self-peel, increasing her all-in threat.
Post level 6 with Lost Chapter, pressure waves and trades more confidently while tracking Lissandra's cooldowns.

Win conditions

Win by farming safely to level 6 and using (R) to zone Lissandra and create pick opportunities.
Use (W) terrain to block Lissandra's escape or force her into your (Q) for crowd control.
Deny Lissandra's engage windows by spacing properly and punishing her cooldowns, especially when (R) and (E) are down.