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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Annie vs Syndra MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Annie

VS

Mid

Syndra

Annie vs Syndra

Confidence mediumUpdated Jun 10, 2026

Overview

Use (R) to find picks and burst Syndra before she can set up spheres for poke.
Pressure Syndra early to deny her calm scaling and poke windows.
Conserve mana by avoiding early (W) pushes to prevent vulnerability to Syndra's harassment.

Trading pattern

Proc your passive stun by weaving (Q) and (W) quickly, finishing with an auto attack.
Punish Syndra when her (E) is on cooldown to avoid her stun threat.
Avoid extended trades when Syndra's spheres are positioned for (E) stun; respect her cooldown.

Danger windows

Respect (E) stun when spheres are positioned; avoid committing during this.
Avoid all-ins when (R) is up and ready to burst you down.
Be ready to punish immediately if Syndra misses her (E) stun, as she becomes vulnerable.

Early game

Play around level 6 to threaten all-ins with (R) and your full burst combo.
Use (E) shield to absorb (Q) and (W) poke and stay in lane longer.
Avoid pushing wave with (W) early to maintain mana and prevent easy Syndra poke.

Power spikes

Level 6 unlocks (R) for strong pick potential and burst damage; use it to force plays.
First completed AP item boosts burst and wave pressure; increase aggression post-item.
Respect Syndra's level 6 (R) and item spikes that improve her poke and control.

Win conditions

Use (R) to initiate picks and follow up with (Q) and (W) burst to secure kills.
Deny Syndra safe farming and punish missed (E) stuns to delay her scaling.
Roam effectively after level 6 to leverage your pick potential and snowball other lanes.

Tip: For Annie vs Syndra, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 10, 2026New matchup