Annie vs Vex MID Matchup Guide | LaneStomp

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Annie

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Mid

Vex

Annie vs Vex

Confidence mediumUpdated Jun 10, 2026

Overview

Annie is a burst mage who must find picks using (R) and punish Vex's immobility outside her ultimate reset.
Apply medium lane pressure to deny Vex's passive fear windows and prevent her from controlling trades.
Use your stun combo to threaten all-ins and force Vex to respect your burst potential.

Trading pattern

Use (Q) + (W) combo to proc your stun and burst Vex quickly before she can react.
Respect Vex's passive fear timing; avoid trading when it's active but punish when missed.
Engage with (R) to initiate or follow up trades when (R) is on cooldown to limit her reset potential.

Danger windows

Avoid trading when Vex's passive fear is active, as it punishes your engage attempts.
Respect (R) window, as she can reset fights and punish overextensions.
Be cautious pushing with (W) on low mana, as it exposes you to Vex's all-in potential.

Early game

Farm safely early to avoid extended trades since Vex has higher early lane pressure and passive fear.
Avoid pushing with (W) early to conserve mana and prevent vulnerability to Vex's all-ins.
Look for level 6 all-ins with (R) when Vex's ultimate is down and she is immobile.

Power spikes

Level 6 with (R) is a major spike; use it to secure picks and force Vex off the wave.
First completed AP item significantly boosts your burst and wave control; pressure more confidently then.
Track Vex's level 6 (R) and her first AP item to avoid unfavorable all-ins during her spikes.

Win conditions

Land (R) to stun and burst Vex with (Q) and (W) before she can respond.
Punish Vex's immobility outside her (R) cooldown by forcing all-ins and denying her passive fear.
Control trades and wave state to limit Vex's passive fear uptime and reduce her lane pressure.