Aphelios vs Vayne ADC Matchup Guide | LaneStomp

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Aphelios

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ADC

Vayne

Aphelios vs Vayne

Confidence mediumUpdated Jun 7, 2026

Overview

The lane turns on Aphelios managing weapon pairs to punish Vayne's short-range CS attempts.
Aphelios wins short-range trades with Calibrum poke and Infernum splash, while Vayne scales better in extended fights.
Hold wave near your side to deny Vayne safe dash windows and force her into risky last hits.

Trading pattern

Step forward to auto or poke when Vayne commits to last-hit and enemy support cannot immediately trade back.
Avoid punishing if enemy support controls brush or threat zone, as (E) can punish overextensions.
Use Calibrum range to harass Vayne during low-health minion moments and Infernum splash to punish grouped minions near her.

Danger windows

Respect (E) cooldown as it enables wall stuns and all-ins when combined with enemy support.
Avoid stepping into brush or river zones without vision to prevent support-enabled engages.
(R) stealth (Q) repositioning creates burst windows; avoid extended trades when (R) is active and support can follow.

Early game

Use first three waves to thin caster minions and punish Vayne's last hits with Calibrum autos.
Avoid pushing past river without support control to prevent (E) wall stun setups.
Track (Q) cooldown to time safe last-hit punish windows without risking support retaliation.

Power spikes

Strong weapon pairs create temporary windows to outpoke or all-in; plan trades around these cycles.
Level 6 (R) amplifies poke or burst depending on active weapon; use (R) only when weapon synergy fits the fight.
First completed marksman item increases safe poke and wave control, enabling better plate and dragon pressure.

Win conditions

Convert Calibrum and Infernum weapon windows into denied CS and forced recalls to build item leads.
Use wave crashes timed with strong weapon pairs to take turret plates and secure dragon vision control.
Rely on support peel and weapon management to scale safely into teamfight DPS, punishing Vayne's short-range all-ins.