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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Cassiopeia vs Galio MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Cassiopeia

VS

Mid

Galio

Cassiopeia vs Galio

Confidence mediumUpdated Jun 10, 2026

Overview

Use controlled mid-range trades to apply poison and force Galio into extended fights where you out-damage him.
Maintain spacing to avoid (W) taunt and (E) engage range.
Manage wave states to deny Galio short trades and prevent his passive lane control.

Trading pattern

Start trades by landing (Q) to apply poison, then spam (E) for sustained damage.
Hold (W) to ground Galio's engage or escape and punish (E) cooldown windows.
Use (R) to punish Galio when he faces you during all-ins after poisoning him.

Danger windows

Respect (W) taunt and (E) knock-up availability for short-range trades.
Avoid committing when (R) is up and can join fights with allies.
Trade aggressively only if Galio misses (E) or (W), exploiting his cooldowns.

Early game

Punish Galio stepping too close with (Q) and (W), respecting his (W) and (E) cooldowns.
Avoid extended trades before level 6 when Galio's crowd control is most threatening.
Hold mid-range spacing to prevent Galio from landing (W) or (E) engages.

Power spikes

Level 6 (R) spikes your kill threat; use it for verified all-ins or defensive resets.
First mana/AP item boosts sustained trade damage; pressure waves confidently after.
Respect Galio's level 6 (R) for map impact and his first durability/AP item for survivability.

Win conditions

Win extended fights by maintaining poison and repeatedly casting (E) while controlling Galio's mobility with (W) and (R).
Deny Galio short trades by spacing outside his (W) and (E) range.
Punish cooldowns on (W) and (E) to force him into passive play and gain lane control.

Tip: For Cassiopeia vs Galio, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 10, 2026New matchup