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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Cassiopeia vs Vex MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Cassiopeia

VS

Mid

Vex

Cassiopeia vs Vex

Confidence mediumUpdated Jun 10, 2026

Overview

This mid-range battle mage matchup favors extended fights where you control space and apply poison.
Deny Vex's passive fear by pressuring early and forcing cooldowns before trades.
Focus on sustained DPS and anti-mobility tools to punish Vex's burst and resets.

Trading pattern

Start trades by landing (Q) or (W) to apply poison, then spam (E) for damage.
Use (W) to block Vex's mobility and force extended fights where you excel.
Avoid trading when (Q) misses or (W) is down to prevent her burst and resets.

Danger windows

Vex is most dangerous when her passive fear is up to disrupt your trades.
Avoid committing when (R) is ready, as she can reset burst combos.
Be cautious when (W) is down, as Vex can use mobility and burst to escape or all-in.

Early game

Use (Q) and (W) to apply poison and punish Vex's fear cooldown early.
Avoid trades without poison to prevent getting burst down by her passive fear.
Hold (W) to ground Vex's dashes and stop her from escaping or re-engaging.

Power spikes

Level 6 (R) lets you punish Vex when she commits facing you; track its cooldown.
First mana/AP item boosts your sustained damage, enabling stronger extended trades.
Respect Vex's level 6 (R) as her main engage and reset tool to avoid all-ins.

Win conditions

Win fights by maintaining poison uptime and repeatedly casting (E) for sustained damage.
Use (W) to control Vex's mobility and force her into unfavorable extended trades.
Capitalize on (R) windows by forcing Vex to face you and secure stuns or kills.

Tip: For Cassiopeia vs Vex, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 10, 2026New matchup