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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Cassiopeia vs Ziggs MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Cassiopeia

VS

Mid

Ziggs

Cassiopeia vs Ziggs

Confidence mediumUpdated Jun 10, 2026

Overview

Use mid-range spacing to apply poison and force extended trades on your terms.
Avoid Ziggs's long-range poke by dodging (Q) and (E) zones before committing.
Aim to out-damage Ziggs in sustained fights by repeatedly casting (E) on poisoned targets.

Trading pattern

Initiate trades by landing (Q) or (W) to apply or maintain poison, then spam (E).
Use (W) to ground Ziggs and block his displacement, punishing his engage attempts.
Punish Ziggs immediately after he uses (W), as his escape tool is down.

Danger windows

Be cautious when (W) is up, as it can knock you away and disrupt trades.
Avoid extended trades without poison or after missing (Q), as your damage drops.
Respect (R) window; it creates a high-risk zone for you to be forced out.

Early game

Use (Q) to apply poison and trade when (Q) and (E) are on cooldown.
Avoid walking into Ziggs's poke zones to prevent early chunk damage.
Conserve mana early to enable extended (E) trades once poison is applied.

Power spikes

Level 6 (R) grants strong all-in potential; use it when Ziggs faces you.
First mana/AP item boosts your sustained damage; pressure more confidently post-item.
Respect Ziggs's level 6 (R) to avoid getting chunked by his long-range burst.

Win conditions

Win lane by keeping Ziggs poisoned and out-damaging him with repeated (E) casts.
Engage all-ins when (R) is available and Ziggs must face you to maximize stun.
Pressure Ziggs after he wastes (W) or misses key abilities to deny his waveclear and poke.

Tip: For Cassiopeia vs Ziggs, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 10, 2026New matchup