Darius vs Vayne TOP Matchup Guide | LaneStomp

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Vayne

Darius vs Vayne

Updated Jun 3, 2026

Overview

Use high early lane pressure to deny Vayne safe farming and force her into risky trades.
Prioritize extended trades where you can stack passive and punish her mobility cooldowns.
This is a snowball vs scaling matchup; snowball early kills to prevent Vayne from reaching her late-game power.

Trading pattern

Use (E) to pull Vayne when she mispositions or uses (Q) forward, then commit to long trades stacking passive.
Prioritize landing outer (Q) for healing to sustain extended fights against her ranged poke.
Avoid short trades where Vayne can kite and reset with (Q) stealth; force her to stay in melee range for passive stacks.

Danger windows

Be cautious when (E) is on cooldown, as Vayne can safely kite and reposition with (Q).
Avoid extended trades when Vayne’s (R) is active, as she can outplay your all-ins with stealth and repositioning.
Watch for ganks if you push without vision; your immobility makes you vulnerable to collapse.

Early game

Start aggressive early to force Vayne to respect your (E) pull and avoid free short trades.
Keep the wave near your side or center to trap Vayne in your pull range.
Avoid pushing without vision to prevent ganks, as your low mobility makes you vulnerable.

Power spikes

Level 6 unlocks (R) execute, enabling lethal all-ins after passive stacks; stack before committing.
First bruiser item spike increases your durability and damage, letting you force longer fights.
Respect Vayne's level 6 (R) stealth repositioning; avoid committing when her (R) is active and space to kite is open.

Win conditions

Deny Vayne safe farming by controlling wave position and threatening (E) pulls.
Force extended melee trades to stack passive and use (R) execute resets to snowball kills.
Use your lane pressure and item spikes to prevent Vayne from scaling into her late-game DPS threat.