Dr. Mundo vs Nasus TOP Matchup Guide | LaneStomp

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Nasus

Dr. Mundo vs Nasus

Updated Jun 3, 2026

Overview

Dr. Mundo should focus on surviving early pressure and farming safely with (Q) to reach his health scaling power spikes.
Avoid giving Nasus a passive lane to stack (Q) freely by applying controlled wave pressure without overcommitting.
This is a scale-focused matchup where Mundo aims to outlast Nasus and become too durable to remove in extended fights.

Trading pattern

Use (Q) to manage spacing and take short trades when it lands, then back off before Nasus can retaliate with (W).
Avoid extended trades before level 6 or when (Q) misses, as Nasus's slow can punish you hard.
Engage longer fights only when (R) is up and you can sustain through Nasus's damage and slows.

Danger windows

Nasus is most dangerous after level 6 with (R) active and enough (Q) stacks; avoid extended trades during this window.
When your passive crowd control block is down, be cautious as (W) slow can lock you down.
Be wary of Nasus forcing all-ins when his (W) slow is available and you lack (R) healing or cooldowns.

Early game

Use (Q) to farm safely and poke Nasus without committing to extended trades before level 6.
Avoid missing (Q) as Mundo's early trading power is low if cleavers don't land.
Respect Nasus's slow (W) and avoid extended trades before you have (R) healing available.

Power spikes

Level 6 (R) is your major spike; use it before burst damage and keep moving through fights to outlast Nasus.
Your first health item significantly boosts durability and damage; pressure side waves to force Nasus to deal with your tankiness.
Respect Nasus's level 6 (R) and high (Q) stacks, which make extended fights dangerous; avoid staying in range too long without (R).

Win conditions

Survive early lane with safe (Q) farming and passive crowd control block to deny Nasus free stacking.
Reach health item spikes and level 6 (R) to absorb damage and outlast Nasus in side-lane fights.
Force Nasus into extended fights where your healing and durability outpace his damage, preventing him from stacking safely.