Hwei vs Vayne ADC Matchup Guide | LaneStomp

Back to matchup selector

Champion

Opponent

RoleGenerate matchup

Hwei

VS

ADC

Vayne

Hwei vs Vayne

Confidence mediumUpdated Jun 7, 2026

Overview

This lane turns on punishing Vayne's short-range last-hit attempts with (Q) poke and CC from (E).
Hwei wins by controlling wave state to deny Vayne safe CS and setting up level 6 all-ins with (R).

Trading pattern

Step forward to auto or (Q) poke when Vayne commits to last hits and her support is out of zone range.
Hold (E) with crowd control to disrupt (E) engage or reposition attempts near walls.
Avoid punishing if enemy support controls brush or can immediately follow trades, as (Q) reposition is dangerous then.

Danger windows

Respect (E) wall stun combined with (R) stealth reposition for sudden all-ins when support is nearby.
Avoid stepping into brush or support threat zones where Vayne can chain (Q) reposition and (E) engage.
Be cautious when (Q) is available to punish overextensions or low-health minion focus.

Early game

Use the first three waves to hold the wave near your side, limiting Vayne's dash and punish angles.
Punish Vayne's last-hit animations with (Q) only if enemy support cannot countertrade or zone.
Track support brush control to decide when to contest low-health caster minions safely.

Power spikes

Level 3 unlocks full spellbook options; use this to adapt (E) for CC or shield against Vayne's engage.
First completed mage item enhances poke and wave control, enabling safer pressure on Vayne's short-range farm.
Level 6 (R) allows for all-in picks; track this to commit when (R) stealth reposition is down.

Win conditions

Convert poke and CC pressure into forced recalls or lost CS to gain item and wave control advantages.
Use wave crashes near turret to deny Vayne plates and force unsafe farm attempts.
Leverage level 6 all-ins with (R) to secure kills or zone Vayne from dragon setups and teamfights.