Kassadin vs Syndra MID Matchup Guide | LaneStomp

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Kassadin

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Mid

Syndra

Kassadin vs Syndra

Updated May 31, 2026

Overview

Kassadin is a scaling assassin who must survive Syndra's poke and burst to reach level 6 safely.
Avoid giving Syndra a passive lane by managing wave and respecting her stun threat with Syndra E.

Trading pattern

Trade minimally pre-6, using Q shield to absorb poke and only short trades when Syndra's Syndra E is down.
After level 6, use R for short controlled trades when Syndra's Syndra E is on cooldown and mana allows safe escape.
Avoid trading if Syndra's Syndra E is available or if low on mana after R use to prevent being locked down.

Danger windows

Pre-6 Kassadin is vulnerable to Syndra's poke and Syndra E stun into burst; avoid extended trades.
Kassadin is in danger when low on mana after using R aggressively without escape options.
Syndra's Syndra E stun availability marks high danger; respect this cooldown to avoid lethal burst.

Early game

Farm safely near tower to minimize damage from Syndra Q and W poke.
Use Q to absorb Syndra's magic damage and avoid extended trades before level 6.
Avoid pushing hard early to reduce risk of Syndra's E stun setup and burst windows.

Power spikes

Kassadin's major spikes are level 6 R and first completed AP item for burst and mobility.
Syndra's major spikes are level 6 Syndra R and first completed mage item increasing poke and burst.
Respect Syndra's spike at level 11 when Syndra Q cooldown lowers and poke threat increases.

Win conditions

Survive early lane by absorbing poke with Q and farming safely to reach level 6.
Use R for short trades and side pressure once level 6 is reached, punishing Syndra's immobility.
Exploit Syndra's lack of mobility and punish missed Syndra E stuns with aggressive R trades.