Lissandra vs Galio MID Matchup Guide | LaneStomp

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Lissandra

VS

Mid

Galio

Lissandra vs Galio

Updated May 31, 2026

Overview

Lissandra's goal is to control short-range trades with W and R to lock down Galio and punish his engage attempts.
Maintain medium lane pressure to prevent Galio from safely roaming or setting up side fights with R.

Trading pattern

Trade when Galio walks into W range to root and follow up with Q slows and R lockdown.
Avoid committing if Galio's W or E is available as they can punish your engage or root attempts.
Use E plus R only when you have reliable ally follow-up or a clear lockdown target to avoid being punished.

Danger windows

Galio is dangerous when W and E are up, threatening taunt and knock-up in short trades.
Avoid engaging if Galio's R is ready and allies can follow up on his engage.
Punish Galio if he wastes E or W cooldowns, as he loses major engage and peel tools.

Early game

Use Q to farm and poke while avoiding extended trades before level 6 when Galio's W and E threaten short trades.
Hold W to root Galio if he steps into melee range and avoid using E aggressively without follow-up.
Track Galio's W and E cooldowns to find safe windows for short trades or wave control.

Power spikes

Lissandra's level 6 R is a major spike for locking down Galio or self-peeling.
Galio's level 6 Galio R increases his map impact and all-in threat, respect its availability.
First completed AP or utility item boosts Lissandra's control and damage potential in lane.

Win conditions

Win by locking Galio down with W and R during his engage cooldowns to punish his short trades.
Deny Galio safe roams by maintaining wave control and punishing his side movements.
Use E to flank or escape, setting up reliable lockdowns with R when jungle or team follow-up is present.