Neeko vs Annie MID Matchup Guide | LaneStomp

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Neeko

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Mid

Annie

Neeko vs Annie

Updated May 31, 2026

Overview

Neeko should use her higher lane pressure to poke Annie and deny her safe farming windows.
Control minion waves to enable E angles and disguise plays, preventing Annie from setting up her burst combos.

Trading pattern

Fish for empowered E angles through minions to lock Annie down and land Q burst quickly.
Respect Annie's passive stun window; trade when her passive stacks are low or after she uses Annie R.
Avoid forcing R unless Annie is grouped or her key cooldowns are down, as she can punish overcommitment.

Danger windows

Annie is most dangerous when her passive stun is stacked and Annie R is available; keep distance and avoid trades then.
If Annie forces you to miss E or wastes mana pushing, she becomes vulnerable to all-ins.
Be cautious when R is down or disguise is tracked, as your engage threat drops and Annie can punish more safely.

Early game

Use E through minions to root Annie and follow up with Q burst before she can retaliate.
Avoid extended trades if E misses, as Annie can punish with her burst and stun.
Use W or passive disguise to create uncertainty and bait Annie's stun proc attempts.

Power spikes

Level 6 R is a major all-in and pick threat; use disguise and minion positioning to threaten or avoid it.
First completed AP item significantly increases Neeko's burst potential, enabling stronger trades.
Respect Annie's level 6 R spike and her burst combo with Annie Q and Annie W when her passive is stacked.

Win conditions

Use E root through minions and Q burst to deny Annie farm and force her out of lane.
Leverage disguise and W clone to create picks or bait Annie's stun for counter-engages.
Turn level 6 into multi-target R threat in teamfights or picks, punishing Annie's limited range and waveclear.