Neeko vs Kassadin MID Matchup Guide | LaneStomp

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Neeko

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Mid

Kassadin

Neeko vs Kassadin

Updated May 31, 2026

Overview

Neeko has strong early lane pressure and should leverage E through minions to punish Kassadin's weak early game.
Focus on denying Kassadin safe scaling by forcing trades before level 6 and using disguise to create kill threats.

Trading pattern

Fish for empowered E roots through minions and immediately burst with Q to punish Kassadin's low early agency.
Respect Kassadin R availability; avoid committing when he can Kassadin R in and out.
Use W and passive disguise to mask engage timing and bait Kassadin's defensive cooldowns.

Danger windows

Kassadin is dangerous post-level 6 with R; avoid close trades when his Kassadin R and mana are available.
Missing E leaves Neeko vulnerable to Kassadin's short trades; play cautiously until E is back.
When Kassadin has mana for repeated R casts, maintain safe spacing and avoid overcommitment.

Early game

Use E angles through minions to root Kassadin and follow up with Q burst before he reaches level 6.
Avoid extended trades if E misses since Kassadin's Q shield and Kassadin R mobility make him dangerous post-6.
Maintain lane pressure to prevent Kassadin from farming safely near his tower.

Power spikes

Neeko's level 6 R unlocks strong all-in and teamfight threat; use it to force Kassadin back or secure picks.
Kassadin's level 6 R grants high mobility and burst; respect this by spacing and not overextending.
Neeko's first completed AP item increases burst potential; leverage this for aggressive trades pre-6 Kassadin.

Win conditions

Use disguise and minion-enhanced E to create pick opportunities and force Kassadin into defensive play.
Deny Kassadin safe farming by punishing pre-6 with E-rooted burst trades.
Leverage R threat in teamfights to control grouped enemies and secure kills before Kassadin can engage.