Neeko vs Zoe MID Matchup Guide | LaneStomp

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Champion

Opponent

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Neeko

VS

Mid

Zoe

Neeko vs Zoe

Updated May 31, 2026

Overview

Neeko has high lane pressure and should use disguise and minion waves to threaten Zoe's skillshot reliance.
Control wave to enable E angles through minions and punish Zoe's missed Zoe E cooldown windows.

Trading pattern

Fish for E through minions to root Zoe, then quickly burst with Q before she can use Zoe R to reposition.
Respect Zoe E cooldown; after she misses Zoe E, step forward aggressively to capitalize.
Avoid trading when Zoe R is available and Zoe E is ready, as her poke and burst are strongest then.

Danger windows

Be cautious when Zoe's Zoe E is off cooldown, as it sets up her burst and sleep CC.
Avoid all-ins when Zoe R is available, as she can dodge your engage and punish with extended poke.
If you miss E, Zoe can punish heavily; retreat and reset before re-engaging.

Early game

Use E through minions early to root Zoe and follow up with Q burst before Zoe can respond.
Avoid extended trades if E misses, as Zoe can punish with her high poke and Zoe Q range.
Use W or passive disguise to create uncertainty and bait Zoe into skillshot mistakes.

Power spikes

Neeko's level 6 R is a major all-in and teamfight threat that can punish Zoe's grouped positioning.
Neeko's first completed AP burst item significantly boosts her kill pressure on Zoe.
Zoe's level 6 R extends her poke range and burst potential, so respect this spike by playing more cautiously.

Win conditions

Use disguise and minion-enhanced E roots to catch Zoe off guard and force her to miss Zoe E.
Punish Zoe's missed Zoe E cooldowns with quick burst trades using Q and follow-up.
Leverage level 6 R to create picks or force Zoe to respect your all-in threat, denying her safe poke angles.