Use Nidalee's very high early game pressure and fast clear to invade Zac's slower early clear and deny his camps before he gains levels.
Prioritize early tempo and poke to contest river Scuttle only when nearby lanes have priority to avoid Zac's long-range engage angles.
This is an early snowball vs late scaling frontline matchup; leverage Nidalee's mobility and poke to punish Zac before he becomes tanky.
Jungle Plan
Invade Zac's jungle camps early when he is on the opposite side of the map and deny his farm to delay his scaling.
Use traps and (Q) spears to control river entrances and force Zac to path defensively, limiting his gank angles.
Prioritize early dragon setup after successful invades and camp steals to convert tempo into objectives before Zac hits tank thresholds.
Danger windows
Beware Zac's early level 2-4 ganks using (E) to engage from fog of war; avoid overextending without vision.
Avoid isolated river fights before level 6 where Zac's knockup (E) and pull (Q) can burst you down.
Be cautious contesting smite fights when low health or Zac's lanes lack priority, as his engage and frontline durability favor him in objective skirmishes.
Early game
Start with a fast clear route to hit level 3 quickly and look for level 3 invades on Zac's weak early clears.
Contest first Scuttle crab only if your lanes have priority and Zac is spotted on opposite side to avoid his long-range (E) engage.
Avoid prolonged river fights early unless you have vision control and health advantage, as Zac's (E) pull and knockup can punish overcommitments.
Power spikes
Nidalee spikes at level 3 with cougar form execute and poke damage; use this to force Zac off camps or secure kills before he tanks up.
Zac spikes after gaining tank items and levels for engage; respect his (E) and (R) knockups in mid to late game teamfights.
Nidalee's high mobility and poke create power spikes when (Q) is up and traps are placed, enabling safe invades and counterjungling.
Win conditions
Use Nidalee's fast clears and poke to invade Zac's jungle repeatedly, denying his farm and delaying his tank scaling.
Control river vision and Scuttle crabs to limit Zac's gank angles and create safe windows for your lanes to snowball.
Convert early tempo leads into dragon and Rift Herald control before Zac's teamfight engage becomes overwhelming.
Tip: For Nidalee vs Zac, read overview, trading pattern, and danger windows first for a fast Jungle lane check.