Pantheon is an early lane bully aiming to deny Vayne a calm scaling lane by using empowered trades and point-and-click stun to control wave and pressure.
Prioritize aggressive lane pressure to prevent Vayne from safely farming and scaling into her late-game dueling power.
Trading pattern
Stack passive then engage with (W) stun followed by empowered (Q) burst, using (E) to block Vayne's counterattack damage.
Punish Vayne immediately after she uses (E) to knock back, as her engage and escape are on cooldown.
Avoid using (W) to engage near walls where Vayne can (E) you for a stun and extended damage.
Danger windows
Be cautious when your (E) is down, as Vayne can punish your burst trades with true damage and kiting.
Respect (E) wall stun threat, especially near terrain; avoid fighting near walls without (E) ready.
After using (W) to engage, your follow-up is predictable; be ready to disengage or block damage with (E) to avoid extended trades.
Early game
Use level 2-3 empowered (Q), (W), and (E) to force short trades and build early health leads before Vayne hits level 6.
Avoid extended trades when (E) is down to prevent Vayne's true damage and kiting from punishing you.
Crash waves after winning trades to deny Vayne farm and create roam opportunities with (R).
Power spikes
Level 2-3: Use empowered (Q), (W), and (E) to force lane dominance and health leads; punish Vayne's weaker early dueling.
Level 6: Use (R) to create cross-map pressure after crashing waves; force Vayne to respect your roam or lose lane control.
Respect Vayne's level 6 stealth repositioning (R) and (Q) for outplays; engage only when you have cooldown advantage.
Win conditions
Use early empowered trades and (W) stun to build lane control and deny Vayne safe scaling.
Crash waves to create roam opportunities with (R) and impact other lanes before Vayne reaches her power spikes.
Maintain pressure to prevent Vayne from freely kiting and scaling; force fights on your terms before her two-item spike.
Tip: For Pantheon vs Vayne, read overview, trading pattern, and danger windows first for a fast Top lane check.
