Sylas vs Lissandra MID Matchup Guide | LaneStomp

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Sylas

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Mid

Lissandra

Sylas vs Lissandra

Updated May 31, 2026

Overview

Sylas is a high-agency melee skirmisher who wants to pressure Lissandra early and deny her safe scaling.
Use E to engage or threaten and W to sustain through trades, forcing Lissandra to respect your all-in potential.

Trading pattern

Use E to initiate trades and follow up with Q and W for sustained damage and healing.
Respect Lissandra W root and R lockdown by disengaging if she commits and R is available.
Punish Lissandra if she uses E aggressively without follow-up by counter-engaging with E and W.

Danger windows

Avoid all-ins when Sylas's E or W is down as Lissandra can punish your melee range.
Respect Lissandra's R availability as it can lock you down or negate your engage.
Be cautious if Lissandra's E is used aggressively without follow-up, as it can be a bait to punish your engage.

Early game

Start pressuring with E to engage and Q-W combos once level 3 is reached for strong trades.
Avoid extended trades when W or E is on cooldown to prevent being punished by Lissandra's poke and root.
Maintain lane pressure to prevent Lissandra from safely farming and setting up her E engages.

Power spikes

Sylas spikes at level 3 with full Q-W-E combo and at level 6 if a valuable enemy ultimate is available to R.
First completed AP item increases Sylas's skirmish damage and sustain.
Lissandra's major spike is level 6 with R for lockdown, which Sylas must respect.

Win conditions

Use E to engage and force extended trades with W sustain and stolen ultimates to out-skirmish Lissandra.
Deny Lissandra safe farming by maintaining lane pressure and punishing her cooldowns.
Capitalize on windows when Lissandra's R or E is down to all-in or force her out of lane.