Vayne vs Tristana ADC Matchup Guide | LaneStomp

Back to matchup selector

Champion

Opponent

RoleGenerate matchup

Vayne

VS

ADC

Tristana

Vayne vs Tristana

Confidence mediumUpdated Jun 7, 2026

Overview

The lane hinges on Vayne punishing Tristana's short-range CS attempts with (Q) autos and spacing.
Vayne wins extended trades through (W) true damage and (E) wall stuns, while Tristana pressures with level 2 all-ins.
Vayne needs wave states that deny Tristana's passive push and jump windows to safely scale and kite.

Trading pattern

Step forward to auto Tristana during her last-hit animations only if enemy support can't immediately punish.
Use (Q) to reposition and punish Tristana's short-range CS attempts, especially when (W) jump is on cooldown.
Hold (E) to (E) Tristana into bot lane walls for stuns, avoiding trades when (E) is down or wave is pushed without vision.

Danger windows

Respect Tristana's level 2 window when (W) jump and (E) burst can combo with support follow-up.
Avoid stepping forward when (R) knockback is ready to interrupt your engage or reposition.
Beware of trades when enemy support controls brush or zone, denying your last-hit punish opportunities.

Early game

Hold the wave near your turret early to limit Tristana's jump angles and reduce her all-in threat.
Punish Tristana's last hits on low-health caster minions when her (W) jump is down and support can't trade back.
Avoid pushing without vision to prevent getting caught by Tristana's level 2 jump with support follow-up.

Power spikes

Level 6 (R) grants stealth (Q) repositioning, letting Vayne outplay Tristana's all-ins with better kiting.
First marksman item spike increases Vayne's dueling and poke, improving last-hit punish windows against Tristana.
Two-item spike turns Vayne into a true damage threat that punishes Tristana's squishiness and forces side-lane pressure.

Win conditions

Convert last-hit punishments into health leads to force Tristana recalls and secure turret plates.
Use wave crashes after Tristana's forced recalls to deny her turret pressure and reset timing.
Scale safely into side-lane duels where Vayne's true damage and (E) wall stuns dominate isolated fights.