Vayne vs Warwick TOP Matchup Guide | LaneStomp

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Warwick

Vayne vs Warwick

Updated Jun 4, 2026

Overview

Use ranged spacing and (Q) repositioning to deny Warwick melee access and avoid extended trades.
Maintain high lane pressure to prevent Warwick from using his sustain and engage tools effectively.
Focus on scaling through safe farming and punishing Warwick's engage cooldowns to become a side-lane dueling threat.

Trading pattern

Trade from max range using autos and (Q) to maintain spacing and avoid (Q) healing and follow.
Hold (E) to counter Warwick's engage or (E) fear, aiming to stun him against terrain.
Avoid using (Q) forward when (R) or (E) are available to prevent being caught in suppression or fear.

Danger windows

Warwick is dangerous when his (E) damage reduction and fear are up; avoid extended trades during this.
Be cautious when (R) is available for suppression; do not overextend or use (Q) aggressively.
After pushing without vision, you are vulnerable to ganks or Warwick's all-ins; keep wave control and ward accordingly.

Early game

Keep the wave on your side to avoid being forced into melee range where Warwick excels.
Avoid pushing without vision to reduce vulnerability to ganks and (R) all-in.
Use (E) to punish Warwick's engage attempts by knocking him into walls and disrupting his follow-up.

Power spikes

Level 6 (R) empowers your dueling and stealth repositioning; use (R) when you have space to kite and punish Warwick's engages.
Two-item spike significantly increases your true damage; pressure side lanes and kite well to exploit Warwick's weaker scaling.
Respect Warwick's level 6 (R) suppress engage; maintain vision and sidestep to avoid lockdown.

Win conditions

Deny Warwick extended melee trades by using (E) to punish his engages and (Q) to maintain spacing.
Scale safely by farming under pressure and hitting your two-item power spike to dominate side-lane duels.
Use (R) stealth and repositioning to outplay Warwick's suppression and force him into unfavorable fights.