Vayne vs Yasuo TOP Matchup Guide | LaneStomp

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Yasuo

Vayne vs Yasuo

Updated Jun 4, 2026

Overview

Use ranged spacing and (Q) repositioning to control Yasuo's engage attempts and avoid his mobility around minions.
Prioritize denying Yasuo's wave control and avoid pushing without vision to prevent ganks and hard engages.
This lane is a scaling duel where Vayne seeks to outscale and pressure Yasuo in side lanes post-level 6.

Trading pattern

Trade by auto-attacking from max range, using (Q) to reposition and avoid (Q) tornado knockup and (R) follow-up.
Punish Yasuo when his (W) is down by stepping forward for short trades and use (E) to (E) him into walls.
Avoid pushing the wave without vision as Yasuo can exploit ganks and engage more reliably after (E) cooldowns.

Danger windows

Yasuo is most dangerous when he has minion waves to dash through and (W) available to block your projectiles.
Be cautious during Yasuo's level 2 power spike and when his (R) is ready to follow up on knockups.
Avoid pushing without vision to reduce vulnerability to Yasuo's all-ins and jungle ganks.

Early game

Hold (E) to punish Yasuo's engage attempts near walls and avoid using (Q) forward when Yasuo's mobility is ready.
Keep the wave in a safe state to deny Yasuo easy (E) dashes and prevent him from stacking (Q) for knockups.
Respect Yasuo's level 2 power spike by avoiding extended trades until you have cooldowns and spacing advantage.

Power spikes

At level 6, use (R) for stealth repositioning and empowered dueling to outplay Yasuo's all-ins.
After your two-item spike, pressure side lanes with vision and kite space to punish Yasuo's melee reliance.
Respect Yasuo's level 2 (Q)+(E) combo and level 6 (R) availability by playing cautiously and avoiding forced trades.

Win conditions

Use (Q) stealth repositioning during (R) to kite Yasuo and punish his engage cooldowns.
Control wave states to deny Yasuo mobility and force him into unfavorable trades near walls for (E) stuns.
Reach your two-item power spike to dominate side-lane duels and leverage true damage against Yasuo's melee threats.