Vayne vs Ziggs ADC Matchup Guide | LaneStomp

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Vayne

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ADC

Ziggs

Vayne vs Ziggs

Confidence mediumUpdated Jun 7, 2026

Overview

This lane turns on Vayne punishing Ziggs's short-range CS attempts with (Q) autos and (E) terrain stuns.
Vayne wins extended trades through true damage and mobility, while Ziggs controls lane with poke and waveclear.
Vayne needs space to kite and avoid Ziggs's poke, aiming to scale into side-lane duels and anti-tank DPS.

Trading pattern

Step forward to auto Ziggs during his last-hit animations on caster minions if enemy support is out of range.
Use (Q) to reposition and punish Ziggs's predictable CS paths, avoiding (Q) forward into his (W) displacement threat.
Hold (E) to (E) Ziggs into bot lane walls after he wastes (W) or overextends for CS.

Danger windows

Respect (W) cooldown; engage only when it's down to avoid displacement and turret executes.
Avoid stepping into poke range when (Q) and (E) are up and enemy support controls brush or engage zones.
Be cautious during (R) availability as it can burst low-health targets and force defensive resets.

Early game

Hold the wave near your side to reduce Ziggs's poke angles and deny safe last hits.
Punish Ziggs when he steps up for caster minion last hits, only if enemy support can't immediately trade back.
Avoid pushing early without vision to prevent gank vulnerability and losing control of (E) terrain stuns.

Power spikes

Level 6 (R) grants stealth on (Q) and stronger dueling; use it to outplay Ziggs's poke and all-ins.
First marksman item spike lets you punish Ziggs harder on CS attempts and improves wave control.
Two-item spike turns Vayne into a potent side-lane threat against tanks, forcing Ziggs to rely on numbers.

Win conditions

Convert CS leads from last-hit punishments into item spikes to pressure side lanes and objectives.
Use wave crashes after recalls to take turret plates and force Ziggs under tower, limiting his poke angles.
Scale safely into late game to leverage (R) stealth repositioning and true damage for teamfight DPS and duels.