Vladimir vs Lissandra MID Matchup Guide | LaneStomp

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Vladimir

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Mid

Lissandra

Vladimir vs Lissandra

Updated Jun 1, 2026

Overview

Vladimir has low early agency and lane pressure, so focus on surviving and farming safely against Lissandra's medium early pressure.
Prioritize sustaining with Q and avoid giving Lissandra free engages with her W root and R lockdown by respecting her crowd control windows.

Trading pattern

Take short trades around empowered Q, but only when Lissandra's W and R are on cooldown.
Save W to dodge Lissandra's W root or R lockdown rather than using it for minor trades.
Punish Lissandra if she uses E forward without follow-up by stepping up with empowered Q trades.

Danger windows

Lissandra is most dangerous when her R is available to lock you down or self-peel.
Avoid extended trades or all-ins when your W is down, as you lose your untargetability and sustain.
Respect Lissandra's W root and E engage cooldowns to prevent getting caught in her crowd control chain.

Early game

Use Q to sustain through Lissandra's poke and avoid extended fights before level 6.
Avoid committing when Lissandra's W is up, as it punishes melee trades heavily.
Stay behind minions to reduce damage from Lissandra Q poke and watch for her E engage attempts.

Power spikes

Vladimir's major spikes are level 6 R and first completed AP item, enabling strong all-ins and burst.
Respect Lissandra's level 6 R and first completed AP or utility item, which increase her lockdown and engage threat.
Mid-game cooldown reductions also boost Vladimir's trading and all-in potential.

Win conditions

Survive early lane with Q sustain and avoid forced W usage to keep your defensive cooldown ready.
Scale into mid-game with your R and AP items to threaten grouped fights and burst Lissandra or her team.
Punish Lissandra's cooldowns on W and R by taking short empowered Q trades and forcing her to play reactively.