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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Zilean vs Cassiopeia MID Matchup Guide | LaneStomp

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Champion

Opponent

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Zilean

VS

Mid

Cassiopeia

Zilean vs Cassiopeia

Confidence mediumUpdated Jun 10, 2026

Overview

Use double bomb setups to zone Cassiopeia and control mid-range spacing.
Prioritize speeding your ADC or yourself to dodge (W) and avoid her sustained trades.
Hold (R) to counter Cassiopeia's burst or all-in attempts, forcing her to hesitate.

Trading pattern

Set bombs on minions near Cassiopeia to force her out of position or miss (Q) poison.
Use (E) speed to engage or disengage trades around her (W) zone.
Punish missed (Q) by stepping forward with double bombs and speed to pressure her cooldowns.

Danger windows

Respect (R) stun when facing her during all-in attempts.
Avoid standing in her (W) zone which grounds your mobility and sets up her trades.
Be cautious when (Q) poison lands, as she can follow up with sustained (E) damage.

Early game

Contest level 2 power spike by landing (Q) bombs before Cassiopeia can apply poison.
Use (E) speed to reposition and avoid her (Q) and (W) poke early.
Avoid extended trades before level 3 when double bomb threat is weaker and (R) is unavailable.

Power spikes

Level 2 unlocks your bomb plus speed combo; use it to contest wave and trades aggressively.
Level 3 enables double bomb setups; coordinate with ADC to maximize poke windows.
Level 6 (R) gives you clutch revive; play for all-ins or peel around this timing.

Win conditions

Deny Cassiopeia's extended trades by zoning her with bombs and speed manipulation.
Use (R) to negate her burst and force her to waste cooldowns or switch targets.
Coordinate with your ADC to capitalize on your speed boosts and double bomb stuns for kills or tower pressure.

Tip: For Zilean vs Cassiopeia, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 10, 2026New matchup